Nature and composition: ZINCIDONE® is the zinc salt of the L-Pyrrolidone Carboxylic Acid (L-PCA). L-PCA is obtained by the cyclization of the L-glutamic acid, an amino acid of plant origin.
Nom CTFA: Zinc PCA
Concept: Zinc : a universal antiseborrheic and essential oligo !
Its antiseptic activity limits bacterial colonization
The L-PCA, : physiological all-purpose agent for a better bio-availability
Mode of action: Known for its action in inhibiting 5-α-reductase, zinc is a specific trace element for seboregulation. Zincidone®, a
combination of zinc and L-PCA, helps regulate the activity of the sebaceous glands and reduces the level of skin sebum in vivo. Its action on bacterial proliferation, notably on Propionibacterium acnes, helps limit the resulting irritation.
Tests performed :
Anti 5-a-réductase activity in vitro
Seboregulating activity in vivo
Bacterial proliferation activity
Recommended dose: 0.1 to 1%